Alessandra Bertoldo
Faculty
alessandra.bertoldo@unipd.it
+39-049-827-7694
Room 311 – 3rd floor – DEI/A
Short Bio
Alessandra Bertoldo is Full Professor in Bioengineering at the Department of Information Engineering, University of Padova, Italy; since 2022, she is Director of the Padova Neuroscience Center, University of Padova, Italy, and since 2017 she is Coordinator of the Master’s Degree Program in Bioengineering and of the Bachelor’s Degree Program in Biomedical Engineering (in Italian: Presidente del CCS aggregato in Ingegneria Biomedica e Bioingegneria).
She has a Master degree in Electronics Engineering, University of Padova, Italy and a PhD in Bioengineering, Politecnico di Milano (Polytechnic University of Milan), Milan, Italy.
Her research interests are mainly related to the development of mathematical models for analysis and control of biological systems and to the quantification of functional positron emission tomography and magnetic resonance images. Current personal and collaborative research activities include: Connectomics (functional, structural, effective, and molecular connectomics), Multimodal Fusion in neuroimaging, Mathematical models for quantitative PET studies, Methods for magnetic resonance functional imaging)
Currently, she teaches “Imaging for Neuroscience” in the Msc in Bioengineering of the Department of Information Engineering, and “Statistical methods for Bioengineering” in the Msc in Bioengineering of the Department of Information Engineering.
She is member of the board of the Doctoral School on Neuroscience (Padova Neuroscience Center, University of Padova). Since November 2015, she is member of the IEEE-EMBC Technical Committee on Biomedical Imaging and Image Processing.
Additional information:
- Molecular Imaging of Brain Connectivity: https://molecularconnectivity.com/
- Padova Neuroscience Center: https://pnc.unipd.it/
- Citations: https://scholar.google.it/citations?user=m0GuxsoAAAAJ&hl=it
Selected Publications
All Publications
PRIN-MURST |
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| PRIN 2000 Modellistica e imaging quantitativo del sistema serotoninergico con Tomografia ad Emissione di Positroni (Principal investigator: Claudio Cobelli) |
Co-investigator |
| PRIN 2004 Modelli e metodi per lo studio delle malattie neurodegenerative con tomografia ad emissione di positroni (Principal investigator: Claudio Cobelli) |
Co-investigator |
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National Institutes of Health, USA |
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| NIH/NIDDK “Multi-tracer PET Quantification of Insulin Action in Muscle” (2002-2006; Principal investigator: David E. Kelley) | DK-60555-01 |
| NIH/NIBIB “Resource Facility for Population Kinetics” (2003-2008; Principal investigator: P. Vicini) | P41 EB-001975 |
| NIH/NIDDK “Multi-Tracer Pet Quantitation of Insulin Action” (2007-2010; Principal investigator: Bret H Goodpaster) | DK-60555-02 |
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European Union |
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| UE Programme FP4-BIOMED 2 “Prediction of shock status using open flow approaches with biosensor detection” (1997-2001; Principal Investigator: Pankaj Vadgama) | Project ID: BMH4972726 |
| UE Programme FP7 “DIAdvisor: Personal Glucose Predictive Diabetes Advisor” | Project ID: 216592 |
| UE Programme FP7 “AP@home: Bringing the Artificial Pancreas Home” | Project ID: 247138 |
| UE Programme FP7 IMI Call (Innovative Medicines Iniziative) “SUMMIT: SUrrogate markers for Micro- and Macro-vascular hard endpoints for Innovative diabetes Tools) | Project ID: 115006 |
| UE Programme FP7 – “MOSAIC – Models and simulation techniques for discovering diabetes influence factors” | Project ID: 600914 |
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University of Padova |
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| 2000 Progetto Giovani Ricercatori “Analisi quantitativa del metabolismo da immagini PET: nuovi metodi di stima parametrica”, (Principal investigator Giovanni Sparacino) | Co-investigator |
| 2003 Progetto Giovani Ricercatori “Modelli non lineari ad effetti misti per la quantificazione di immagini di Tomografia ad Emissione di Positroni | Principal investigator |
| 2007 Progetti di Ricerca di Ateneo “Sviluppo di un modello elettrico a parametri distribuiti dell’interfaccia cellula/elettrodo per cellule di mammifero coltivate in vitro” | Principal investigator |
| 2013 Progetti di Ricerca di Ateneo “Neuroimaging Genetics: Models and Methods to Integrate Brain Phenotype and Genotype” | Principal investigator |
| 2007-2009 Progetti di Eccellenza – Fondazione CARIPARO “MIcrofluidics laboratory for Scientific and Technological Applications”, (Principal investigator: Michele Maggini) | Co-investigator |
| Progetti strategici di Ateneo 2008 “AACSE: Algorithms and Architectures for Computational Science and Engineering” (Principal investigator: Bilardi Gianfranco) | Co-investigator |
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Italian Ministry of Health |
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| NET-2013-02355313 (3 years project) Magnetic resonance imaging in drug-refractory temporal lobe epilepsy: standardization of advanced structural and functional protocols at 3T, to identify hippocampal and extra-hippocampal abnormality (Principal investigator: Paolo Vitali) |
Co-investigator |
Selected Publications
All Publications
2008
Data modeling and simulation Book
2008.
Novel reference region model reveals increased microglial and reduced vascular binding of11C-(R)-PK11195 in patients with Alzheimer's disease Journal Article
In: Journal of Nuclear Medicine, vol. 49, no. 8, pp. 1249-1256, 2008.
2007
Increased binding potential of [11C]PK11195 in Alzheimer disease using a new SRTM accounting for vascular binding Journal Article
In: Journal of Cerebral Blood Flow and Metabolism, vol. 27, no. SUPPL. 1, pp. PP01-03M, 2007.
Muscle glucose transport and phosphorylation in type 2 diabetic, obese nondiabetic, and genetically predisposed individuals Journal Article
In: American Journal of Physiology - Endocrinology and Metabolism, vol. 292, no. 1, pp. E92-E100, 2007.
2006
The glucose minimal model: Population vs individual parameter estimation Conference
vol. 6, no. PART 1, 2006.
Identification of IVGTT minimal glucose model by nonlinear mixed-effects approaches. Journal Article
In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 5049-5052, 2006.
Parametric imaging of acetylcholinesterase activity with PET: Evaluation of different methods Conference
vol. 6, no. PART 1, 2006.
Interactions between delivery, transport, and phosphorylation of glucose in governing uptake into human skeletal muscle Journal Article
In: Diabetes, vol. 55, no. 11, pp. 3028-3037, 2006.
Dose-responsive insulin regulation of glucose transport in human skeletal muscle Journal Article
In: American Journal of Physiology - Endocrinology and Metabolism, vol. 290, no. 6, pp. E1124-E1130, 2006.